HCID 178422930, compound → HCID 178422931, compound

HRID 979193Notes

Reaction equation

HRID 979193 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[N:10]=[CH:11][NH:12][CH:13]=2)[CH:5]=[CH:6][C:7]=1[NH2:8].[C:14]([N:16]=[C:17](CC)[O-])#[N:15]>C(O)C>[C:14]([NH:16][CH:17]=[N:8][C:7]1[CH:6]=[CH:5][C:4]([C:9]2[N:10]=[CH:11][NH:12][CH:13]=2)=[CH:3][C:2]=1[CH3:1])#[N:15]

Participants

4

Reactant 2

HCID 178422930HCID 178422930, compoundHCID 178460292HCID 178460292, compound

Product 1

HCID 178422931HCID 178422931, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 4-(3-Methyl-4-amino-phenyl)-1-H-imidazole (15.9 g) and N-Cyano-ethylformimidate (9 g) in ethanol (100 ml) was stirred overnight at room temperature. The solid which crystallized out was filtered off and dried to give 11.3 of the desired compound. M.p. 200°-202° C.

Workup

  1. customThe solid which crystallized out
  2. filtrationwas filtered off
  3. customdried

Sources & evidence

ORD record
ord-e58f36613e184dbb9dd4ad2ac86bd4c9
Source dataset
uspto-grants-1987_05
Patent number
US04666932

Reaction notes

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