HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 979194Generated: November 1, 2026
Cyanamide → N-Cyano-N'-[4-(1H-imidazol-2-yl)phenyl]methanimidamide
https://huagongshe.com/reaction/979194
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyanamide | HCID 9864 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 4-(1H-Imidazol-2-yl)aniline | HCID 23506927 | — |
| Product | N-Cyano-N'-[4-(1H-imidazol-2-yl)phenyl]methanimidamide | HCID 20201830 | 62.2% |
Reaction Steps
A mixture of 2-(4-amino-phenyl)-1-H-imidazole (3.1 g), cyanamide (0.8 g) and triethyl orthoformate (3.6 g) was heated at 150° C. for a few minutes. The product which crystallized out was filtered off, washed with ethanol and dried to give 2.5 g of the title compound, M.p. 228°-229° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04666932 |
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| Source dataset | uspto-grants-1987_05 |
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| ORD ID | ord-6b37d5cd0c2a45cbbd51768450d45946 |
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| Source note | uspto-grants-1987_05 |
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