Water → HCID 20202084, compound

HRID 979303Notes

Reaction equation

HRID 979303 reaction equation
[CH:1]1[C:14]2[C:5]([O:6][C:7]3[C:12]([N:13]=2)=[CH:11][CH:10]=[CH:9][CH:8]=3)=[CH:4][C:3](=[O:15])[CH:2]=1.[Cl:16]Cl.O>C(O)(=O)C>[Cl:16][C:4]1[C:3](=[O:15])[CH:2]=[CH:1][C:14]2[C:5]=1[O:6][C:7]1[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=1)[N:13]=2

Participants

5

Reactant 3

HCID 962WaterHCID 24526ChlorineHCID 114834Phenoxazinone

Product 1

HCID 20202084HCID 20202084, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

To a solution of 1.2 g of 3H-phenoxazin-3-one in acetic acid (25 ml) was added K2Cr2O7 (3.7 g). A solution of chlorine in acetic acid was added dropwise to the resulting suspension. After disappearance of the starting material, as monitored by TLC, the reaction mixture was poured into 200 ml of H2O and the resulting precipitate was filtered (1.2 g) and chromatographed on silica gel to yield the title compound.

Workup

  1. filtrationthe resulting precipitate was filtered (1.2 g)
  2. customchromatographed on silica gel

Sources & evidence

ORD record
ord-9cd040a5fb1546fea51a863e04a35a03
Source dataset
uspto-grants-1987_05
Patent number
US04667032

Reaction notes

Loading…