Triethyl phosphite → HCID 20199962, compound

HRID 979397Notes

Reaction equation

HRID 979397 reaction equation
Br[CH2:2][CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([C:9]([CH3:16])=[CH:10][C:11](=[O:15])[O:12]2)=[CH:7][CH:6]=1.[CH2:17]([O:19][P:20]([O:24]CC)[O:21][CH2:22][CH3:23])[CH3:18]>>[CH2:17]([O:19][P:20]([CH2:2][CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([C:9]([CH3:16])=[CH:10][C:11](=[O:15])[O:12]2)=[CH:7][CH:6]=1)(=[O:24])[O:21][CH2:22][CH3:23])[CH3:18]

Participants

3

Reactant 2

HCID 31215Triethyl phosphiteHCID 3444002H-1-Benzopyran-2-one, 7-(2-bromoethoxy)-4-methyl-

Product 1

HCID 20199962HCID 20199962, compound

Procedure

28.32 g. (0.1 mole) 7-(2'-bromo-ethyl-oxy)-4-methyl-coumarin and 33.23 g. (0.2 mole) triethylphosphite are heated under stirring for 1 hour. The reaction mixture is then cooled. The end-product is separated from the contaminations by removing same by vacuum distillation. The bottom product is a yellow, thick, oily substance of weight 11.9 g. (0.0035 mole), nD31 =1.5619.

Workup

  1. temperatureThe reaction mixture is then cooled
  2. customThe end-product is separated from the contaminations
  3. customby removing same by vacuum distillation

Sources & evidence

ORD record
ord-18dc529e802344ab845dcfe1a433e6f8
Source dataset
uspto-grants-1987_05
Patent number
US04668274

Reaction notes

Loading…