反应详情

温度

70 °C

N-Cyclohexyl-N-methyl-2-aminoethanol (25 g) is added dropwise to thionyl chloride (120 cc) and then the mixture is heated for 24 hours at 70° C. After the excess thionyl chloride has been distilled off, the orange oil obtained is stirred into ethyl ether (200 cc) to give a white solid, which is separated off by filtrattion and then washed with ether. 2-(N-Cyclohexyl-N-methyl-amino)-1-chloroethane (30 g) is obtained in the form of a white solid melting at 154° C.

1. distillationAfter the excess thionyl chloride has been distilled off
2. customthe orange oil obtained
3. customto give a white solid, which
4. customis separated off by filtrattion
5. washwashed with ether