Pyridine → 1-{4-[4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-trifluoromethylpentyl]-2,6-dimethylpiperazin-1-yl}ethanone
Reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH3:1][CH:2]1[CH2:3][N:4]([CH2:9][C:10]([C:11]([F:12])([F:13])[F:14])([CH2:15][C:16]([CH3:17])([CH3:18])[c:19]2[c:20]([O:26][CH3:27])[cH:21][cH:22][c:23]([F:25])[cH:24]2)[OH:28])[CH2:5][CH:6]([CH3:8])[NH:7]1.[CH3:35][C:36](=[O:37])[O:38][C:39](=[O:40])[CH3:41].[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[CH3:1][CH:2]1[CH2:3][N:4]([CH2:9][C:10]([C:11]([F:12])([F:13])[F:14])([CH2:15][C:16]([CH3:17])([CH3:18])[c:19]2[c:20]([O:26][CH3:27])[cH:21][cH:22][c:23]([F:25])[cH:24]2)[OH:28])[CH2:5][CH:6]([CH3:8])[N:7]1[C:36]([CH3:35])=[O:37]Participants
5
Sources & evidence
- ORD record
- ord-4207e9e1603f4d14924e93ee006a4d43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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