Hydrochloric Acid → HCID 53781212, compound

Participants

Reaction Steps

DL-N-(Aminocarbonyl)-2,3-dimethyl-6-nitrophenylalanine Potassium cyanate (17.5 g, 0.21 mol) was added to stirred solution of DL-2,3-dimethyl-6-nitrophenylalanine hydrochloride (15 g, 0.05 mol) in water (125 mL). The mixture was heated on a steam bath for 30 minutes, cooled and acidified with 2N hydrochloric acid solution. The precipitate was filtered off, washed with water and dried in air to give DL-N-(aminocarbonyl)-2,3-dimethyl-6-nitrophenylalanine as a hydrate (16.0 g, 100%), m.p. 223°-224° C. (dec). Spectral data were in accord with the assigned structure.

Provenance & Evidence