Hydrochloric Acid → HCID 86741544, compound

Participants

Reaction Steps

A solution of 5-(2-acetoxyethyl)-2-sulfamoyl benzo[b]thiophene (1.8 g, 0.006 mol), ethanol (50 ml) and 10% NaOH (50 ml) was heated at reflux. After 4.5 h, the mixture was poured into 3N HCl (150 ml) and extracted with ethyl acetate (3X). The organic extracts were washed with saturated Na2CO3, dried, filtered and concentrated to dryness to yield 1.5 g (97%) of product, m.p. 162°-164° C.

Provenance & Evidence