Sodium Azide → HCID 21283484, compound

Participants

Reaction Steps

Under nitrogen, a solution of 5-(2-bromoethyl)-2-sulfamoylbenzo[b]thiophene (1.2 g, 0.0037 mol), NaN3 (0.6 g, 0.0092 mol) and DMF (25 ml) was heated at 100° C. After 18 hours, the solution was cooled, poured into H2 0, and filtered to yield 0.8 g of product. The filtrate was extracted with ethyl acetate (2×). The organic layers were dried, filtered and concentrated to dryness to yield an additional 0.4 g of product (75%).

Provenance & Evidence