2-Chloro-3-pyridylamine → [2-[(3-Amino-2-pyridinyl)amino]phenyl](2-pyridinyl)methanone

HRID 979601Notes

Reaction equation

HRID 979601 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1)=[O:9].[NH2:16][C:17]1[C:18](Cl)=[N:19][CH:20]=[CH:21][CH:22]=1>>[NH2:16][C:17]1[C:18]([NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=2)=[O:9])=[N:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 805282-Chloro-3-pyridylamineHCID 27565322-(2-Aminobenzoyl)pyridine

Product 1

HCID 20200329[2-[(3-Amino-2-pyridinyl)amino]phenyl](2-pyridinyl)methanone

Procedure

The title compound is prepared by reacting (2-aminophenyl)(2-pyridinyl)methanone, as prepared by Schofield, K., J. Chem. Soc. 1949, 2408-12, with 3-amino-2-chloropyridine.

Workup

  1. customas prepared by Schofield, K

Sources & evidence

ORD record
ord-f1fe6138d2d74afc98934224a22532fb
Source dataset
uspto-grants-1987_05
Patent number
US04668675

Reaction notes

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