HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-[(3-Amino-2-pyridinyl)amino]phenyl](3-thienyl)methanone → 6-(3-thienyl)11H-pyrido[2,3-b][1,4]benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-[(3-Amino-2-pyridinyl)amino]phenyl](3-thienyl)methanone | HCID 20200359 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Product | 6-(3-thienyl)11H-pyrido[2,3-b][1,4]benzodiazepine | HCID 135626370 | — |
Reaction Steps
Following the procedure of Example 20, [2-[(3-amino-2-pyridinyl)amino]phenyl](3-thienyl)methanone is heated with para toluene sulfonic acid catalyst in organic solvent while removing water in a Dean-Stark trap to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04668675 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-c2828567cdab4f41a4ced35d5852b3d9 |
| Source note | uspto-grants-1987_05 |