HCID 21427949, compound → HCID 13548054, compound

Participants

Reaction Conditions

Reaction Steps

418.8 g of 94% pure α-nonylacrolein oxime, 1,030 g of o-xylene, 94.6 g of 95% pure α-nonylacrylonitrile and 13.9 g (2 mol %, based on oxime) of Cu(II) 2-ethylhexanoate were heated at 130° C. A vigorous exothermic reaction began; after this reaction had abated, stirring was continued for a further 1.5 hours at 110° C. Analysis by gas chromatography showed that 98.8% of the oxime used had been converted. 1.2 liters of petroleum ether were added to the reaction mixture, the latter was then cooled to -20° C., and the crude amide precipitated was filtered off under suction. Recrystallization from cyclohexane gave 332 g (84%) of α-nonylacrylamide as colorless crystals of melting point 80°-81° C.

Provenance & Evidence