2-Phenylethanol → HCID 20164408, compound

Participants

Reaction Steps

Into a 250 cc reaction flask equipped with stirrer, thermometer and reflux condenser are placed 120 grams phenylethyl alcohol; 26 grams 3-mercaptopropionic acid; and 0.5 grams of para-toluene sulphonic acid. With stirring, the reaction mass is heated to reflux and refluxed for a period of 8 hours. At the end of the 8 hour period, the reaction mass is mixed with 200 ml diethyl ether and washed with two 100 ml portions of 10% aqueous sodium bicarbonate followed by one 100 ml portion of water. The organic phase is separated and dried and the solvents are recovered on a Buchi evaporator. The resulting product is then distilled using a micro distillation apparatus yielding the following fractions:

Provenance & Evidence