Sodium Azide → HCID 178492595, compound

HRID 979767Notes

Reaction equation

HRID 979767 reaction equation
[N-:1]=[N+:2]=[N-:3].[Na+].[CH3:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[N:15]=[C:16]=[S:17]>O>[CH3:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[N:15]1[C:16]([SH:17])=[N:3][N:2]=[N:1]1

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 1424662,5-Dimethoxyphenyl isothiocyanate2×

Product 1

HCID 178492595HCID 178492595, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Sodium azide was dissolved in water in an amount corresponding to 1.1 equivalent to 2,5-dimethoxyphenylisothiocyanate, and cooled. Thereto, 2,5-dimethoxyphenylisothiocyanate was slowly added. After the conclusion of the addition, the mixture was stirred at a room temperature for 30 minutes and then, it was refluxed for 4 hours as heat was applied thereto. At the conclusion of the reaction, the reaction mixture was cooled and neutralized to produce crystals of 1-(2,5-dimethoxyphenyl)-5-mercaptotetrazole.

Workup

  1. temperaturecooled
  2. additionAfter the conclusion of the addition
  3. temperatureit was refluxed for 4 hours
  4. temperatureas heat
  5. customAt the conclusion of the reaction
  6. temperaturethe reaction mixture was cooled

Sources & evidence

ORD record
ord-e5e7b21f9fbf420ea7dd978bd607ecec
Source dataset
uspto-grants-1987_01
Patent number
US04634660

Reaction notes

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