HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-{Bicyclo[2.2.1]heptan-2-yl}ethan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Norborn-2-ylacetic acid | HCID 79139 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 2-{Bicyclo[2.2.1]heptan-2-yl}ethan-1-amine | HCID 20222870 | 35% |
Reaction Steps
Norbornane-2-acetic acid was treated with SOCl2, then with NH3. The resulting amine was reduced with LiAlH4 to give the desired intermediate. Yield: 35%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04634701 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-89ff04e69db24ab5aa91db85b2fdded3 |
| Source note | uspto-grants-1987_01 |