Sodium borohydride → HCID 70435016, compound

HRID 979809Notes

Reaction equation

[C:1]([CH2:3][O:4][C:5]1[C:14]([O:15][CH3:16])=[CH:13][C:12]([F:17])=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]=[CH:10]2)#[N:2].[BH4-].[Na+]>>[C:1]([CH2:3][O:4][C:5]1[C:14]([O:15][CH3:16])=[CH:13][C:12]([F:17])=[C:11]2[C:6]=1[CH2:7][CH2:8][CH2:9][CH2:10]2)#[N:2]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 70434616HCID 70434616, compound

Product 1

HCID 70435016HCID 70435016, compoundYield 66%

Procedure

The product from Example 68 (2.5 g) was reduced with sodium borohydride (1.3 g) using the procedure of Example 2 to afford the product (1.65 g) in 66% yield.

Sources & evidence

ORD record: ord-7fe0b8884e8e498b8e4c5316b4c1c53b
Source dataset: uspto-grants-1987_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04634705

Reaction notes

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