Chloroform → HCID 20223012, compound

Participants

Reaction Steps

A solution of 6-hydroxy-1-tetralone (1.62 g) in chloroform (100 ml) was treated with t-butyl hypochlorite (2.3 ml) dropwise at room temperature. After 1.5 hours the reaction was diluted with chloroform and quenched with aqueous sodium bisulfite. The organic layer was separated, washed with brine, dried and evaporated in vacuo affording the desired product in 96% yield. Recrystallized from hot ethyl acetate yielded (1 g) of needles.

Provenance & Evidence