Ethyl chloroformate → Ethyl 2,3-dihydro-7-(2-propen-1-yl)-1H-indole-1-carboxylate

Participants

Reaction Conditions

Reaction Steps

The product from Example 113 (0.8 g) was dissolved in pyridine (3 ml), cooled to 0° C. and ethyl chloroformate (0.77 ml) was added. After 10 minutes, the reaction was quenched with water and extracted with diethylether. The organic layer was separated and washed with cold 2% hydrochloric acid, 5% sodium bicarbonate, brine and dried. The solvent was evaporated in vacuo affording the desired compound in 90% yield as an oil.

Provenance & Evidence