Methanol → HCID 86741189, compound

HRID 979821Notes

Reaction equation

HRID 979821 reaction equation
[CH3:1][S:2][C:3]1[C:11]2[C:10]3[CH2:12][CH2:13][CH2:14][CH:15]([C:16]#[N:17])[C:9]=3[CH:8]=[CH:7][C:6]=2[NH:5][CH:4]=1.CO.[CH2:20](N)[CH2:21][NH2:22]>C(Cl)Cl>[NH:17]1[CH2:20][CH2:21][N:22]=[C:16]1[CH:15]1[C:9]2[CH:8]=[CH:7][C:6]3[NH:5][CH:4]=[C:3]([S:2][CH3:1])[C:11]=3[C:10]=2[CH2:12][CH2:13][CH2:14]1

Participants

5

Reactant 3

HCID 887MethanolHCID 3301EthylenediamineHCID 20223005HCID 20223005, compound

Product 1

HCID 86741189HCID 86741189, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The product from Example 123 (1.9 g) was dissolved in methylene chloride (35 ml) and methanol (1.5 ml) and reacted with ethylenediamine (3.5 ml) as in Example 35 giving the desired product (1.38 g).

Sources & evidence

ORD record
ord-d5aa7bfbaff9477fa54c957b3f72b76e
Source dataset
uspto-grants-1987_01
Patent number
US04634705

Reaction notes

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