Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Tert-Butyl hypochlorite | HCID 521297 | — |
| Reactant | N-(5,6,7,8-Tetrahydro-4-methyl-5-oxo-2-naphthalenyl)acetamide | HCID 20223013 | — |
| Product | HCID 20222977 | HCID 20222977 | 50% |
Reaction Steps
A solution of the product from Example 130 (1.78 g) in chloroform (50 ml) at -78° C. was treated with t-butylhypochlorite (2 ml) in two portions. The reaction was stirred at -78° C. for 10 minutes. Following the procedure of Example 95 the desired product was obtained in 50% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04634705 |
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| Source dataset | uspto-grants-1987_01 |
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| ORD ID | ord-fe3aabb36e8647bfb0c9990d4d1b5753 |
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| Source note | uspto-grants-1987_01 |
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