Methanol → HCID 131715007, compound

Participants

Reaction Steps

The product from Example 135 (0.5 g) was dissolved in methanol (50 ml) and concentrated sulfuric acid (3 ml) was added. The reaction was refluxed for 4 hours and solvent was evaporated to one-half the volume. The concentrated reaction mixture was diluted with benzene (50 ml) and washed with brine, and aqueous sodium bicarbonate. The organic layer was separated, dried and evaporated affording the desired ester in 89% yield.

Provenance & Evidence