Hydrochloric Acid → HCID 70430209, compound

Participants

Reaction Steps

To the product of Step C above (1.125 g) in 3 ml of ethyl acetate at 0° C. was added 6 ml of 5.8M hydrogenchloride in ethyl acetate, an the mixture was kept at 0° C. for 45 minutes. It was then concentrated to dryness; ether (20 ml) was added, and the crystalline hydrochloride salt was collected by filtration and washed with ether: 715 mg (80%) m.p. 175°-8° C.; TLC Rf =0.47 silica gel 4:1:1-n-butanol:water:acetic acid.

Provenance & Evidence