HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanal → 1-(2,3,5-Trimethyl-6-pyrazinyl)-1-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanal | HCID 527 | — |
| Reactant | Trimethylpyrazine | HCID 26808 | — |
| Reactant | Acetone hexane | HCID 21880519 | — |
| Product | 1-(2,3,5-Trimethyl-6-pyrazinyl)-1-propanone | HCID 577940 | 48% |
Reaction Steps
The reaction of trimethylpyrazine and freshly distilled propionaldehyde is carried out as described in Example I on the same molar scale. Preparative thick layer chromatography (2000μ silica gel GF, developed in 5% acetone/hexane) of the crude reaction product gives a 48% yield of 1-(2,3,5-trimethyl-6-pyrazinyl)-1-propanone (mp 65°-67° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04635652 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-5db9e4108e4e47afb11712a9b0b1966b |
| Source note | uspto-grants-1987_01 |