Benzenesulfonamide → HCID 178527591, compound

HRID 980152Notes

Reaction equation

HRID 980152 reaction equation
[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)=[CH:6][CH:5]=1)([OH:3])=O.[C:18]1([S:24]([NH2:27])(=[O:26])=[O:25])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>CN(C)C=O.O>[C:18]1([S:24]([N:27]=[C:1]([C:4]2[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][N:11]3[CH:15]=[CH:14][N:13]=[CH:12]3)=[CH:6][CH:5]=2)[OH:3])(=[O:26])=[O:25])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 7370BenzenesulfonamideHCID 53001Dazoxiben

Product 1

HCID 178527591HCID 178527591, compound

Reagents, catalysts & solvents 1

HCID 21962138N,N-Dimethylformamide--water (1/1)Solvent

Procedure

Treatment of 1-[2-(4-carboxyphenoxy)ethyl]imidazole with N,N'-carbonyldiimidazole followed by benzenesulphonamide as described in Example 36 above gave N-benzenesulphonyl-4-[2-(1-imidazolyl)ethoxy]benzenecarboximidic acid, m.p. 250°-252° C. (from N,N-dimethylformamide/H2O). Found: C, 58.17; H, 4.60; N, 11.08. C18H17N3O4S requires: C, 58.21; H, 4.61; N, 11.31%.

Sources & evidence

ORD record
ord-8ea7c6059ed84665aa364921d6ea7058
Source dataset
uspto-grants-1987_01
Patent number
US04636500

Reaction notes

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