Water → 3,4-Dihydro-6-hydroxy-2-methoxy-4-oxo-N-phenyl-5-pyrimidinecarboxamide

Participants

Reaction Steps

To a solution of 4,6-dihydroxy-2-methoxypyrimidine (6 g) in dry dimethyl sulfoxide was added triethylamine (5.9 ml). The solution was brought to 60° and phenyl isocyanate (5 g) was added; the solution was maintained at 80°-90° for two hours, cooled and water added slowly to cause precipitation.

Provenance & Evidence