HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Chloroethyl)dibenzylamine → 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Chloroethyl)dibenzylamine | HCID 5820 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2,3-Dihydroxybenzoate | HCID 75484 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester | HCID 53929446 | — |
Reaction Steps
2,3-dihydroxybenzoic acid methyl ester is reacted in the presence of potassium carbonate in acetonitrile with 1.1 equivalents of 1-dibenzylamino-2-chloroethane for 18 hours at 82°. The crude 3-(2-dibenzylaminoethoxy)salicylic acid methyl ester obtained after working up is put to further use without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04636511 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-fd70129b19b24615a369c47f36b987a1 |
| Source note | uspto-grants-1987_01 |