Water → HCID 12822473, compound

Participants

Reaction Steps

A solution of phenylmethyl[2-[5-[[(methylsulphonyl)amino]methyl]-1H-indol-3-yl]ethyl]carbamate (0.02 g) in dry THF (1 ml) was added to a stirred suspension of lithium aluminium hydride (0.1 g) in THF (2 ml) and the mixture was refluxed under nitrogen for 3 h. The mixture was cooled and excess reagent was decomposed by the addition of 10% water in THF. Salt and ethyl acetate (20 ml) were added and the organic layer was dried (Na2SO4) and evaporated in vacuo to leave the title compound as a brown oil (0.015 g).

Provenance & Evidence