HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoro-m-phenylenediamine dihydrochloride → 2,3,4,5-Tetrahydro-2-[3-(3-pyridinyl)propyl]-1H-pyrido[4,3-b]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 1H,2H,3H,4H,5H-pyrido[4,3-b]indole | HCID 723230 | — |
| Reactant | 4-Pyridinylbutyl bromide | HCID 53406386 | — |
| Reactant | 3-Pyridinylpropyl bromide hydrobromide | HCID 67937748 | — |
| Product | 2,3,4,5-Tetrahydro-2-[3-(3-pyridinyl)propyl]-1H-pyrido[4,3-b]indole | HCID 13772448 | — |
Reaction Steps
The title compound was prepared following the procedure of Example 1 with the exception 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole was used instead of 8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole and 3-pyridinylpropyl bromide hydrobromide replaced the 4-pyridinylbutyl bromide salt. The product was converted to the dihydrochloride salt; mp 223°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04636563 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-9ae7cce3fd4b478daa52dd4efb45c599 |
| Source note | uspto-grants-1987_01 |