HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Vinylquinoline → 8-Chloro-2,3,4,5-tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido-[4,3-b]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Vinylquinoline | HCID 69875 | — |
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido(4,3-b)indole | HCID 904970 | — |
| Product | 8-Chloro-2,3,4,5-tetrahydro-2-[2-(2-quinolinyl)ethyl]-1H-pyrido-[4,3-b]indole | HCID 13772454 | — |
Reaction Steps
The title compound was prepared following the procedure of Example 2 with the exception that 8-chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole was used instead of 8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole and 2-vinylquinoline was used instead of 2-vinylpyridine. The product was converted to the dihydrochloride salt; mp 187°-190° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04636563 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-441a28ad3a6e45588118df93f72bff82 |
| Source note | uspto-grants-1987_01 |