m-Chloroperbenzoic acid → HCID 178440664, compound

Participants

Reaction Steps

In 10 ml of chloroform was dissolved 0.8 g of 2-benzylthio-4-(3,5-di-tert-butyl-4-hydroxyphenyl)imidazole and then 0.35 g of m-chloroperbenzoic acid was added to the solution at room temperature. After the reaction was over, the reaction mixture was washed with a diluted aqueous alkali solution, dried, and concentrated under reduced pressure. The residue formed was subjected to silica gel chromatography and eluted with chloroform. The fraction thus obtained was concentrated udner reduced pressure and the residue was recrystallized from cyclohexane to provide 0.3 g of 2-benzylsulfinyl)-4-(3,5-di-tert-butyl-4-hydroxyphenyl)imidazole.

Provenance & Evidence