HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-benzyloxycarbonyl-N-butyl-2-pyrrolidinecarboxamide → (S)-N-Butylpyrrolidine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-benzyloxycarbonyl-N-butyl-2-pyrrolidinecarboxamide | HCID 13564336 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (S)-N-Butylpyrrolidine-2-carboxamide | HCID 22691332 | 97.7% |
Reaction Steps
In 140 ml of methanol was dissolved 4.41 g of compound (30) and the compound was hydrogenated using 426 mg of 10% palladium-carbon as a catalyst. The catalyst was filtered off and the filtrate was concentrated to provide 2.41 g of (S)-N-butyl-2-pyrrolidinecarboxamide (31).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04636567 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-c1097bf92120475598882f1feb356f3e |
| Source note | uspto-grants-1987_01 |