HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- → HCID 131715024, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Reactant | HCID 71777655 | HCID 71777655 | — |
| Product | HCID 131715024 | HCID 131715024 | 74.1% |
Reaction Steps
Boc-Phe-OH (26.5 g, 100 mmol) was coupled to H-Gly-Ala-OCH3.HCl (19.6 g, 100 mmol) using a mixed anhydride procedure. After crystallization from ethyl acetate:hexane, 30.2 g of Boc-Phe-Gly-Ala-OCH3 (m.p. 126.4°-127.8°) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04636492 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-2d6a0b4cbcd848228fabee24d3aea095 |
| Source note | uspto-grants-1987_01 |