HCID 16219556, compound → HCID 131714614, compound

Participants

Reaction Steps

Z-Phe-Ser(OCH2C6H5)-Ala-LeuCH2Cl was prepared by coupling Z-Phe-Ser(OCH2C6H5)-Ala-OH (1.37 g, 2.5 mmol) to H-LeuCH2Cl.HCl by a mixed anhydride coupling procedure substantially similar to that used for the preparation of Z-Phe-Gly-Leu-LeuCH2Cl in Procedure C, above. Product was obtained as a crystalline solid, 0.98 g (m.p. 167°-168°). Anal: Calcd. for C37H45N4O7 : C, 64.09; H, 6.56; N, 8.08; Found: C, 64.22; H, 6.38; N, 8.08.

Provenance & Evidence