HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → Phenyl 5-bromo-2-hydroxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 5-Bromosalicylic acid | HCID 6972 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Phenyl 5-bromo-2-hydroxybenzoate | HCID 266984 | — |
Reaction Steps
80 ml of thionyl chloride was gradually added to a benzene suspension of 217 g of 5-bromosalicyclic acid and 113 g of phenol, followed by refluxing for ten hours under heating. After distilling off the benzene, ice-water was added to the residue, and the precipitate formed was collected by filtration, followed by drying. Yield: 210 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04637902 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-fff0888236b54b86aff40ea01a9b6ec8 |
| Source note | uspto-grants-1987_01 |