HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylcarbamoyl Chloride → 5-Bromosalicylhydroxamic Acid N,N-Dimethylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-Bromosalicylhydroxamic acid | HCID 22046 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Bromosalicylhydroxamic Acid N,N-Dimethylcarbamate | HCID 86741217 | — |
Reaction Steps
81 ml of triethylamine was gradually added to a dimethylformamide solution containing 136 g of 5-bromosalicylhydroxamic acid prepared as in (2-2) above and 54 ml of N,N-dimethylcarbamyl chloride at room temperature (about 20°-30° C.), then stirred for 10 hours. This solution was poured into ice-water to collect the precipitate by filtration followed by drying. Yield: 102 g; mp. 118°-119° C. (dec.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04637902 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-12510d497a8c4a0194d2eb60ff0048ea |
| Source note | uspto-grants-1987_01 |