HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → 1-(2-Methyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 12322222 | HCID 12322222 | — |
| Solvent | 1,2-Dichloroethylene | HCID 10900 | — |
| Product | 1-(2-Methyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)propan-1-one | HCID 13785272 | 58% |
Reaction Steps
83 gr. (0.5M) of 2-methyl-thiochromane are treated with 43.2 ml of propionyl chloride (0.5M) in the presence of 73 gr. of AlCl3 (0.55M) in 750 ml of 1,2-dichloroethylene in the already described preceding examples. 64 gr. of 2-methyl-6-propionyl-thiochromane are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04638070 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-6c402af002e24e068761c584b82b1080 |
| Source note | uspto-grants-1987_01 |