反应详情

In 200 ml of ethanol is dissolved 17 g of ethyl 3-(3,4,5,6-tetrahydro-2H-pyran -4-yl)acrylate, and a catalytic reduction reaction is carried out at ordinary temperature and at atmospheric pressure using 4 g of 10% palladium-carbon (50% in water) as a catalyst. After absorption of hydrogen stops, the catalyst is removed by filtration, and the filtrate is concentrated under reduced pressure. The residue is distilled under vacuum to give 15 g (bp 121-123°/16 mmHg)of ethyl 3-(3,4,5,6-tetrahydro-2H-pyran -4-yl)propionate as an oily material.

1. customa catalytic reduction reaction
2. customAfter absorption of hydrogen
3. customthe catalyst is removed by filtration
4. concentrationthe filtrate is concentrated under reduced pressure
5. distillationThe residue is distilled under vacuum