HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Dioxide → 1-Benzylazetidine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | N-Benzyl-3-cyanoazetidine | HCID 19814762 | — |
| Solvent | Barium hydroxide | HCID 6093286 | — |
| Product | 1-Benzylazetidine-3-carboxylic acid | HCID 3161318 | 80% |
Reaction Steps
0.5 g of 2B in 10 ml of saturated barium hydroxide solution was heated under reflux for 30 hours. The mixture was cooled, saturated with gaseous carbon dioxide and filtered. The solvent was removed from the filtrate under reduced pressure to give 1-benzylazetidine-3-carboxylic acid (2C), in 80% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04639334 |
| Source dataset | uspto-grants-1987_01 |
| ORD ID | ord-8b109640117f40bc988c2ddc10aae23d |
| Source note | uspto-grants-1987_01 |