HRID980789

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68442

1H-Imidazole-4,5-dicarboxylic acid

C5H4N2O4

结构：CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H]4O[C@@]45C[C@@H](O)CC[C@]5(C)[C@H]3CC[C@]12C

HCID227037

Cholesterol alpha-oxide

C27H46O2

PRODUCTS

生成物

结构：CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H]4O[C@@]45C[C@@H](O)CC[C@]5(C)[C@H]3CC[C@]12C.O=C(O)c1nc[nH]c1C(=O)O

HCID131715038

未命名化合物

PROCEDURE

实验过程

Following the procedure of Example 29 cholesterol 5α,6α-epoxide and α,β-imidazole dicarboxylic acid in 1:2 molar ratio under alkaline conditions produce the desired product. ##STR10##

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-be8c848a050946f7aa1dac4eb23c174d
来源数据集: uspto-grants-1987_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04639420
来源说明: uspto-grants-1987_01

反应 SMILES

[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:8])[CH3:7].[CH:30]1[NH:34][C:33]([C:35]([OH:37])=[O:36])=[C:32]([C:38]([OH:40])=[O:39])[N:31]=1>>[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:7])[CH3:8].[CH:30]1[NH:31][C:32]([C:38]([OH:40])=[O:39])=[C:33]([C:35]([OH:37])=[O:36])[N:34]=1