m-Chloroperbenzoic acid → HCID 13772001, compound

Participants

Reaction Steps

To a solution of 2.07 grams (0.01 mole) of benzo[4,5]cyclohepta[1,2-b]pyridin-5-one in 25 milliliters of chloroform was added dropwise, a solution of 2.0 grams (0.01 mole) of m-chloroperbenzoic acid in 30 milliliters of chloroform and the resulting solution stirred for 7 hours at room temperature. At this time an additional 0.5 gram of m-chloroperbenzoic acid was added and the mixture stirred overnight at room temperature. The resulting reaction mixture was washed successively with two 100 milliliter portions of 10 percent aqueous sodium hydroxide and two 100 milliliter portions of water and then dried over magnesium sulfate. The dried solution was filtered to remove the drying agent and the chloroform was vaporized to obtain 2.23 grams of a benzo[4,5]cyclohepta[1,2-b]pyridin-5-one N-oxide intermediate.

Provenance & Evidence