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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 980881Generated: November 3, 2026

Ethyl orthoformate → Ethyl 2,3-dimethoxy-6-nitrobenzoate

https://huagongshe.com/reaction/980881

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl orthoformateHCID 31214—
Reactant2,3-Dimethoxy-6-nitrobenzoic acidHCID 12762379—
SolventIsopropanolHCID 3776—
ProductEthyl 2,3-dimethoxy-6-nitrobenzoateHCID 1374991380%

Reaction Steps

Condensation of 2,3-dimethoxy-6-nitrobenzoic acid (1 eg) with (1.5 eg) of triethyl orthoformate gave after isopropanol crystallization an 80% yield of the title compound, mp 120°-122° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04639518
Source datasetuspto-grants-1987_01
ORD IDord-97e71b77524b47c09ca5ee818f805799
Source noteuspto-grants-1987_01