Phosphoric Acid → HCID 86741241, compound

HRID 980904Notes

Reaction equation

HRID 980904 reaction equation
S(=O)(=O)(O)O.[O:6]=[CH:7][C:8]1[CH:16]=[CH:15][C:13]([OH:14])=[C:10]([O:11][CH3:12])[CH:9]=1.[P:17](=[O:21])([OH:20])([OH:19])[OH:18]>>[P:17](=[O:18])([OH:21])([OH:20])[OH:19].[O:6]=[CH:7][C:8]1[CH:16]=[CH:15][C:13]([OH:14])=[C:10]([O:11][CH3:12])[CH:9]=1

Participants

4

Reactant 3

HCID 1004Phosphoric AcidHCID 1118Sulfuric AcidHCID 1183Vanillin2×

Product 1

HCID 86741241HCID 86741241, compound

Procedure

In this method, the lipid containing plasma is heated with concentrated sulfuric acid; then vanillin and phosphoric acid are added to yield a pink color. The unsaturated components of a lipid specimen is assumed to be oxidized to ketones, the ketones then condensing with vanillin under the influence of acid catalysis. Following the assumed condensation reaction, dehydration of an aldol-type intermediate is further assumed to yield a more highly unsaturated product that absorbs visible light at wavelength 520 nm. By using olive oil as a standard, the total lipid removal from plasma in the process was measued, with the following results (Table IV):

Workup

  1. additionIn this method, the lipid containing plasma
  2. customto yield a pink color
  3. customthe assumed condensation reaction, dehydration of an aldol-type intermediate
  4. customto yield a more highly unsaturated product that
  5. customabsorbs visible light at wavelength 520 nm
  6. customthe total lipid removal from plasma in the process
  7. customwith the following results (Table IV)

Sources & evidence

ORD record
ord-2384613adf1a42698b8a27fc75e3f14f
Source dataset
uspto-grants-1987_01
Patent number
US04639513

Reaction notes

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