Maleic Anhydride → Dimethylmaleic anhydride

HRID 980922Notes

Reaction equation

HRID 980922 reaction equation
[C:1]1(=[O:7])[O:6][C:4](=[O:5])C=C1.N[C:9]1[CH:14]=[CH:13][CH:12]=CN=1>C(O)(=O)C>[CH3:12][C:13]1=[C:14]([CH3:9])[C:4]([O:6][C:1]1=[O:7])=[O:5]

Participants

4

Reactant 2

HCID 7923Maleic AnhydrideHCID 104392-Aminopyridine

Product 1

HCID 13010Dimethylmaleic anhydrideYield 269.6%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

58.0 g (0.5 mol) of maleic anhydride and 4.7 g (0.05 mol) of 2-aminopyridine are boiled under reflux for 48 hours in 200 ml of glacial acetic acid. Working up as in Example 1 affords 17.0 g (54%) of dimethylmaleic anhydride with a melting point of 91°-93° C.

Sources & evidence

ORD record
ord-3d9a1ca5b43b463895ff39094e5cbe60
Source dataset
uspto-grants-1987_01
Patent number
US04639531

Reaction notes

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