Sodium Iodide → HCID 14780080, compound

Participants

Reaction Steps

Following the procedure of Preparation 3, but using p-nitrobenzyl 2-[3-(1-t-butyldimethylsilyloxyethyl)-4-methylthio-2-azetidinon-1-yl]-2-chloroacetate (1.272 g), sodium iodide (379 mg) and sodium cyanoborohydride (314 mg) and purifying the crude product by silica gel column chromatography eluted with a 10:1 by the volume mixture of benzene and ethyl acetate, there were obtained 785 mg of the desired compound.

Provenance & Evidence