HCID 54279535, compound → HCID 54564502, compound

Participants

Reaction Steps

4.71 g of 12-isobutoxy-4,8-cyclododecadien-1-ol were dissolved in 50 ml of dichloromethane and 8 g of diatomaceous earth were added to this solution, in suspension. After stirring, 8.05 g of PCC were added in small portions, the reaction mixture having been kept under stirring, at room temperature, for 2 h. Afterwards, the chromium salts were precipitated with ethyl ether and the reaction mixture was filtered on SiO2 and concentrated. Distillation in a bulb-to-bulb apparatus gave 3.43 g of 12-isobutoxy-4,8-cyclododecadien-1-one.

Provenance & Evidence