HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 7-Acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane | HCID 15070017 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane | HCID 15070018 | — |
Reaction Steps
11.8 g (64 mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04990517 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-82984d96c2f842a6949503cd60f56b01 |
| Source note | uspto-grants-1991_02 |