HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperazine → HCID 14700567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperazine | HCID 66057 | — |
| Reactant | 8-Chloro-1-ethyl-7-fluoro-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine-3-carboxylic acid | HCID 14700555 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14700567 | HCID 14700567 | — |
Reaction Steps
1-Ethyl-7-fluoro-8-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-benzo[b][1,8]naphthyridine-3-carboxylic acid is prepared under the conditions of Reference Example 1 but starting from 2.1 g of 8-chloro-1-ethyl-7-fluoro-4-oxo-1,4-dihydro-benzo[b][1,8]naphthyridine-3-carboxylic acid, 20 cm3 of pyridine and 2.4 g of 2-methylpiperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04990515 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-3ad24229199942888894bed36be3b3bd |
| Source note | uspto-grants-1991_02 |