HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 1-[(4-Morpholino)phenylsulphonyl]-2-pyrrolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | (4-Morpholinophenylsulphonylamino)butyric acid | HCID 19811002 | — |
| Product | 1-[(4-Morpholino)phenylsulphonyl]-2-pyrrolidinone | HCID 10470642 | 96.4% |
Reaction Steps
6.2 g of product obtained in Stage A, 6.2 g of sodium acetate and 124 cm3 of acetic anhydride are heated to reflux for 4 hours. After cooling to ambient temperature and evaporating to dryness, the residue is taken up with 50 cm3 of water, filtered, washed with 10 cm3 of water and dried. 5.65 g of expected product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04990531 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-87e291401aea40beac1bbf843329333e |
| Source note | uspto-grants-1991_02 |