HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 981252Generated: October 30, 2026
Hydrochloric Acid → HCID 20071772, compound
https://huagongshe.com/reaction/981252
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Thioanisole | HCID 7520 | — |
| Reactant | Butanoic acid, 4-chloro-4-oxo-, methyl ester | HCID 73888 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | HCID 20071772 | HCID 20071772 | — |
Reaction Steps
Thioanisole (12.4 g) and 1,4-dioxo-4-methoxybutyl chloride (16.5 g) in dichloroethane (100 ml) were cooled to 0° C. and aluminum chloride (16 g) was added, followed by another equivalent (16 g) and the reaction mixture was stirred at 0° C. for 2 hours. Ice was added, followed by 1N HCl. Dichloromethane (100 ml) was then added and the organic layer was separated, washed with water and then brine and dried with Na2SO4. Removal of the solvents yielded the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04990526 |
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| Source dataset | uspto-grants-1991_02 |
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| ORD ID | ord-21ec6c9d41d84206a0858c3d8c29c91a |
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| Source note | uspto-grants-1991_02 |
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