HCID 86744597, compound → HCID 20071812, compound

HRID 981328Notes

Reaction equation

HRID 981328 reaction equation
C(O[N:9]([CH2:21][CH2:22][CH2:23][CH2:24][NH:25]OCC1C=CC=CC=1)[CH2:10][C:11](=C=O)[C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])C1C=CC=CC=1.[H][H]>CO.[Pd]>[NH2:25][CH2:24][CH2:23][CH2:22][CH2:21][NH:9][CH2:10][CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]

Participants

5

Reactant 2

HCID 86744597HCID 86744597, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20071812HCID 20071812, compoundYield 99.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2.49 g (5.14 mmol) of t-butyl 4,9-bisbenzyloxy-carbonyl-4,9-diazanonanoate was dissolved in 20 ml of methanol and 0.3 g of palladium black was added thereto. The obtained mixture was reduced at room temperature under atmospheric pressure in a hydrogen gas stream for three hours. After filtering off the catalyst, the filtrate was concentrated under reduced pressure to thereby give 1.11 g of the aimed compound in the form of an oily product (yield: 100%).

Workup

  1. filtrationAfter filtering off the catalyst
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-15d82fe4312a4f75be97c228d5c8c6ed
Source dataset
uspto-grants-1991_02
Patent number
US04990536

Reaction notes

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